Activin–like kinase–3 activity is important for kidney regeneration and reversal of fibrosis

Molecules associated with TGF-β superfamily such as BMPs and TGF-β are key regulators of inflammation, apoptosis and cellular transitions. Here, we demonstrate that the BMP receptor activin–like kinase 3 (Alk3) is elevated early in response to kidney injury and its deletion in the tubular epithelium...

Descripción completa

Detalles Bibliográficos
Autores principales: Sugimoto, Hikaru, LeBleu, Valerie S., Basukonda, Dattatreyamurty, Keck, Peter, Taduri, Gangadhar, Bechtel, Wibke, Okada, Hirokazu, Carlson, William, Bey, Philippe, Rusckowski, Mary, Tampe, Björn, Tampe, Desiree, Kanasaki, Keizo, Zeisberg, Michael, Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998727/
https://www.ncbi.nlm.nih.gov/pubmed/22306733
http://dx.doi.org/10.1038/nm.2629

Ejemplares similares

Ejemplares similares