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Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization of Cyclopropylidene Bearing 1,5-Enynes
[Image: see text] An enantioselective ring-expanding cycloisomerization of 1,5-enynes bearing a cyclopropylidene moiety has been developed. This methodology provides a new approach to bicyclo[4.2.0]octanes, a structural motif present in many biologically active natural products.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998771/ https://www.ncbi.nlm.nih.gov/pubmed/24684491 http://dx.doi.org/10.1021/ol5007955 |
| _version_ | 1782313412651384832 |
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| author | Zheng, Hongchao Felix, Ryan J. Gagné, Michel R. |
| author_facet | Zheng, Hongchao Felix, Ryan J. Gagné, Michel R. |
| author_sort | Zheng, Hongchao |
| collection | PubMed |
| description | [Image: see text] An enantioselective ring-expanding cycloisomerization of 1,5-enynes bearing a cyclopropylidene moiety has been developed. This methodology provides a new approach to bicyclo[4.2.0]octanes, a structural motif present in many biologically active natural products. |
| format | Online Article Text |
| id | pubmed-3998771 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | American
Chemical Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-39987712015-03-31 Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization of Cyclopropylidene Bearing 1,5-Enynes Zheng, Hongchao Felix, Ryan J. Gagné, Michel R. Org Lett [Image: see text] An enantioselective ring-expanding cycloisomerization of 1,5-enynes bearing a cyclopropylidene moiety has been developed. This methodology provides a new approach to bicyclo[4.2.0]octanes, a structural motif present in many biologically active natural products. American Chemical Society 2014-03-31 2014-04-18 /pmc/articles/PMC3998771/ /pubmed/24684491 http://dx.doi.org/10.1021/ol5007955 Text en Copyright © 2014 American Chemical Society |
| spellingShingle | Zheng, Hongchao Felix, Ryan J. Gagné, Michel R. Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization of Cyclopropylidene Bearing 1,5-Enynes |
| title | Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization
of Cyclopropylidene Bearing 1,5-Enynes |
| title_full | Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization
of Cyclopropylidene Bearing 1,5-Enynes |
| title_fullStr | Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization
of Cyclopropylidene Bearing 1,5-Enynes |
| title_full_unstemmed | Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization
of Cyclopropylidene Bearing 1,5-Enynes |
| title_short | Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization
of Cyclopropylidene Bearing 1,5-Enynes |
| title_sort | gold-catalyzed enantioselective ring-expanding cycloisomerization
of cyclopropylidene bearing 1,5-enynes |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998771/ https://www.ncbi.nlm.nih.gov/pubmed/24684491 http://dx.doi.org/10.1021/ol5007955 |
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