High Antimicrobial Effectiveness with Low Hemolytic and Cytotoxic Activity for PEG/Quaternary Copolyoxetanes

[Image: see text] The alkyl chain length of quaternary ammonium/PEG copolyoxetanes has been varied to discern effects on solution antimicrobial efficacy, hemolytic activity and cytotoxicity. Monomers 3-((4-bromobutoxy)methyl)-3-methyloxetane (BBOx) and 3-((2-(2-methoxyethoxy)ethoxy)methyl)-3-methylo...

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Detalles Bibliográficos
Autores principales: King, Allison, Chakrabarty, Souvik, Zhang, Wei, Zeng, Xiaomei, Ohman, Dennis E., Wood, Lynn F., Abraham, Sheena, Rao, Raj, Wynne, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998775/
https://www.ncbi.nlm.nih.gov/pubmed/24422429
http://dx.doi.org/10.1021/bm401794p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998775/
https://www.ncbi.nlm.nih.gov/pubmed/24422429
http://dx.doi.org/10.1021/bm401794p

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