Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins

The promyelocytic leukemia (PML) protein organizes PML nuclear bodies (NBs), which are stress-responsive domains where many partner proteins accumulate. Here, we clarify the basis for NB formation and identify stress-induced partner sumoylation as the primary NB function. NB nucleation does not rely...

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Detalles Bibliográficos
Autores principales: Sahin, Umut, Ferhi, Omar, Jeanne, Marion, Benhenda, Shirine, Berthier, Caroline, Jollivet, Florence, Niwa-Kawakita, Michiko, Faklaris, Orestis, Setterblad, Niclas, de Thé, Hugues, Lallemand-Breitenbach, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998805/
https://www.ncbi.nlm.nih.gov/pubmed/24637324
http://dx.doi.org/10.1083/jcb.201305148

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