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Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging
The Biomedical Imaging and Therapy (BMIT) beamline at the Canadian Light Source has produced some excellent biological imaging data. However, the disadvantage of a small vertical beam limits its usability in some applications. Micro-computed tomography (micro-CT) imaging requires multiple scans to p...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998813/ https://www.ncbi.nlm.nih.gov/pubmed/24763635 http://dx.doi.org/10.1107/S1600577514003014 |
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author | Martinson, Mercedes Samadi, Nazanin Belev, George Bassey, Bassey Lewis, Rob Aulakh, Gurpreet Chapman, Dean |
author_facet | Martinson, Mercedes Samadi, Nazanin Belev, George Bassey, Bassey Lewis, Rob Aulakh, Gurpreet Chapman, Dean |
author_sort | Martinson, Mercedes |
collection | PubMed |
description | The Biomedical Imaging and Therapy (BMIT) beamline at the Canadian Light Source has produced some excellent biological imaging data. However, the disadvantage of a small vertical beam limits its usability in some applications. Micro-computed tomography (micro-CT) imaging requires multiple scans to produce a full projection, and certain dynamic imaging experiments are not possible. A larger vertical beam is desirable. It was cost-prohibitive to build a longer beamline that would have produced a large vertical beam. Instead, it was proposed to develop a beam expander that would create a beam appearing to originate at a source much farther away. This was accomplished using a bent Laue double-crystal monochromator in a non-dispersive divergent geometry. The design and implementation of this beam expander is presented along with results from the micro-CT and dynamic imaging tests conducted with this beam. Flux (photons per unit area per unit time) has been measured and found to be comparable with the existing flat Bragg double-crystal monochromator in use at BMIT. This increase in overall photon count is due to the enhanced bandwidth of the bent Laue configuration. Whilst the expanded beam quality is suitable for dynamic imaging and micro-CT, further work is required to improve its phase and coherence properties. |
format | Online Article Text |
id | pubmed-3998813 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-39988132014-05-13 Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging Martinson, Mercedes Samadi, Nazanin Belev, George Bassey, Bassey Lewis, Rob Aulakh, Gurpreet Chapman, Dean J Synchrotron Radiat Research Papers The Biomedical Imaging and Therapy (BMIT) beamline at the Canadian Light Source has produced some excellent biological imaging data. However, the disadvantage of a small vertical beam limits its usability in some applications. Micro-computed tomography (micro-CT) imaging requires multiple scans to produce a full projection, and certain dynamic imaging experiments are not possible. A larger vertical beam is desirable. It was cost-prohibitive to build a longer beamline that would have produced a large vertical beam. Instead, it was proposed to develop a beam expander that would create a beam appearing to originate at a source much farther away. This was accomplished using a bent Laue double-crystal monochromator in a non-dispersive divergent geometry. The design and implementation of this beam expander is presented along with results from the micro-CT and dynamic imaging tests conducted with this beam. Flux (photons per unit area per unit time) has been measured and found to be comparable with the existing flat Bragg double-crystal monochromator in use at BMIT. This increase in overall photon count is due to the enhanced bandwidth of the bent Laue configuration. Whilst the expanded beam quality is suitable for dynamic imaging and micro-CT, further work is required to improve its phase and coherence properties. International Union of Crystallography 2014-03-13 /pmc/articles/PMC3998813/ /pubmed/24763635 http://dx.doi.org/10.1107/S1600577514003014 Text en © Mercedes Martinson et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Research Papers Martinson, Mercedes Samadi, Nazanin Belev, George Bassey, Bassey Lewis, Rob Aulakh, Gurpreet Chapman, Dean Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging |
title | Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging |
title_full | Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging |
title_fullStr | Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging |
title_full_unstemmed | Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging |
title_short | Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging |
title_sort | development of a bent laue beam-expanding double-crystal monochromator for biomedical x-ray imaging |
topic | Research Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998813/ https://www.ncbi.nlm.nih.gov/pubmed/24763635 http://dx.doi.org/10.1107/S1600577514003014 |
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