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Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging

The Biomedical Imaging and Therapy (BMIT) beamline at the Canadian Light Source has produced some excellent biological imaging data. However, the disadvantage of a small vertical beam limits its usability in some applications. Micro-computed tomography (micro-CT) imaging requires multiple scans to p...

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Autores principales: Martinson, Mercedes, Samadi, Nazanin, Belev, George, Bassey, Bassey, Lewis, Rob, Aulakh, Gurpreet, Chapman, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998813/
https://www.ncbi.nlm.nih.gov/pubmed/24763635
http://dx.doi.org/10.1107/S1600577514003014
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author Martinson, Mercedes
Samadi, Nazanin
Belev, George
Bassey, Bassey
Lewis, Rob
Aulakh, Gurpreet
Chapman, Dean
author_facet Martinson, Mercedes
Samadi, Nazanin
Belev, George
Bassey, Bassey
Lewis, Rob
Aulakh, Gurpreet
Chapman, Dean
author_sort Martinson, Mercedes
collection PubMed
description The Biomedical Imaging and Therapy (BMIT) beamline at the Canadian Light Source has produced some excellent biological imaging data. However, the disadvantage of a small vertical beam limits its usability in some applications. Micro-computed tomography (micro-CT) imaging requires multiple scans to produce a full projection, and certain dynamic imaging experiments are not possible. A larger vertical beam is desirable. It was cost-prohibitive to build a longer beamline that would have produced a large vertical beam. Instead, it was proposed to develop a beam expander that would create a beam appearing to originate at a source much farther away. This was accomplished using a bent Laue double-crystal monochromator in a non-dispersive divergent geometry. The design and implementation of this beam expander is presented along with results from the micro-CT and dynamic imaging tests conducted with this beam. Flux (photons per unit area per unit time) has been measured and found to be comparable with the existing flat Bragg double-crystal monochromator in use at BMIT. This increase in overall photon count is due to the enhanced bandwidth of the bent Laue configuration. Whilst the expanded beam quality is suitable for dynamic imaging and micro-CT, further work is required to improve its phase and coherence properties.
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spelling pubmed-39988132014-05-13 Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging Martinson, Mercedes Samadi, Nazanin Belev, George Bassey, Bassey Lewis, Rob Aulakh, Gurpreet Chapman, Dean J Synchrotron Radiat Research Papers The Biomedical Imaging and Therapy (BMIT) beamline at the Canadian Light Source has produced some excellent biological imaging data. However, the disadvantage of a small vertical beam limits its usability in some applications. Micro-computed tomography (micro-CT) imaging requires multiple scans to produce a full projection, and certain dynamic imaging experiments are not possible. A larger vertical beam is desirable. It was cost-prohibitive to build a longer beamline that would have produced a large vertical beam. Instead, it was proposed to develop a beam expander that would create a beam appearing to originate at a source much farther away. This was accomplished using a bent Laue double-crystal monochromator in a non-dispersive divergent geometry. The design and implementation of this beam expander is presented along with results from the micro-CT and dynamic imaging tests conducted with this beam. Flux (photons per unit area per unit time) has been measured and found to be comparable with the existing flat Bragg double-crystal monochromator in use at BMIT. This increase in overall photon count is due to the enhanced bandwidth of the bent Laue configuration. Whilst the expanded beam quality is suitable for dynamic imaging and micro-CT, further work is required to improve its phase and coherence properties. International Union of Crystallography 2014-03-13 /pmc/articles/PMC3998813/ /pubmed/24763635 http://dx.doi.org/10.1107/S1600577514003014 Text en © Mercedes Martinson et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Papers
Martinson, Mercedes
Samadi, Nazanin
Belev, George
Bassey, Bassey
Lewis, Rob
Aulakh, Gurpreet
Chapman, Dean
Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging
title Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging
title_full Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging
title_fullStr Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging
title_full_unstemmed Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging
title_short Development of a bent Laue beam-expanding double-crystal monochromator for biomedical X-ray imaging
title_sort development of a bent laue beam-expanding double-crystal monochromator for biomedical x-ray imaging
topic Research Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998813/
https://www.ncbi.nlm.nih.gov/pubmed/24763635
http://dx.doi.org/10.1107/S1600577514003014
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