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Contribution of Network Connectivity in Determining the Relationship between Gene Expression and Metabolite Concentration Changes
One of the primary mechanisms through which a cell exerts control over its metabolic state is by modulating expression levels of its enzyme-coding genes. However, the changes at the level of enzyme expression allow only indirect control over metabolite levels, for two main reasons. First, at the lev...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998873/ https://www.ncbi.nlm.nih.gov/pubmed/24762675 http://dx.doi.org/10.1371/journal.pcbi.1003572 |