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Contribution of Network Connectivity in Determining the Relationship between Gene Expression and Metabolite Concentration Changes

One of the primary mechanisms through which a cell exerts control over its metabolic state is by modulating expression levels of its enzyme-coding genes. However, the changes at the level of enzyme expression allow only indirect control over metabolite levels, for two main reasons. First, at the lev...

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Detalles Bibliográficos
Autores principales: Zelezniak, Aleksej, Sheridan, Steven, Patil, Kiran Raosaheb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998873/
https://www.ncbi.nlm.nih.gov/pubmed/24762675
http://dx.doi.org/10.1371/journal.pcbi.1003572