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Folliculin Regulates Ampk-Dependent Autophagy and Metabolic Stress Survival
Dysregulation of AMPK signaling has been implicated in many human diseases, which emphasizes the importance of characterizing AMPK regulators. The tumor suppressor FLCN, responsible for the Birt-Hogg Dubé renal neoplasia syndrome (BHD), is an AMPK-binding partner but the genetic and functional links...
Autores principales: | Possik, Elite, Jalali, Zahra, Nouët, Yann, Yan, Ming, Gingras, Marie-Claude, Schmeisser, Kathrin, Panaite, Lorena, Dupuy, Fanny, Kharitidi, Dmitri, Chotard, Laëtitia, Jones, Russell G., Hall, David H., Pause, Arnim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998892/ https://www.ncbi.nlm.nih.gov/pubmed/24763318 http://dx.doi.org/10.1371/journal.pgen.1004273 |
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