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Longer Telomere Length in COPD Patients with α(1)-Antitrypsin Deficiency Independent of Lung Function
Oxidative stress is involved in the pathogenesis of airway obstruction in α(1)-antitrypsin deficient patients. This may result in a shortening of telomere length, resulting in cellular senescence. To test whether telomere length differs in α(1)-antitrypsin deficient patients compared with controls,...
Autores principales: | Saferali, Aabida, Lee, Jee, Sin, Don D., Rouhani, Farshid N., Brantly, Mark L., Sandford, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998943/ https://www.ncbi.nlm.nih.gov/pubmed/24763308 http://dx.doi.org/10.1371/journal.pone.0095600 |
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