Cargando…

Molecular Recognition of CCR5 by an HIV-1 gp120 V3 Loop

The binding of protein HIV-1 gp120 to coreceptors CCR5 or CXCR4 is a key step of the HIV-1 entry to the host cell, and is predominantly mediated through the V3 loop fragment of HIV-1 gp120. In the present work, we delineate the molecular recognition of chemokine receptor CCR5 by a dual tropic HIV-1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tamamis, Phanourios, Floudas, Christodoulos A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999033/ https://www.ncbi.nlm.nih.gov/pubmed/24763408 http://dx.doi.org/10.1371/journal.pone.0095767

Ejemplares similares

Elucidating a Key Anti-HIV-1 and Cancer-Associated Axis: The Structure of CCL5 (Rantes) in Complex with CCR5
por: Tamamis, Phanourios, et al.
Publicado: (2014)

Insights into the Structure, Correlated Motions, and Electrostatic Properties of Two HIV-1 gp120 V3 Loops
por: López de Victoria, Aliana, et al.
Publicado: (2012)

Elucidating a Key Component of Cancer Metastasis: CXCL12 (SDF-1α) Binding to CXCR4
por: Tamamis, Phanourios, et al.
Publicado: (2014)

Highly Accurate Structure-Based Prediction of HIV-1 Coreceptor Usage Suggests Intermolecular Interactions Driving Tropism
por: Kieslich, Chris A., et al.
Publicado: (2016)

Short Communication: HIV-1 Variants That Use Mouse CCR5 Reveal Critical Interactions of gp120's V3 Crown with CCR5 Extracellular Loop 1
por: Platt, Emily J., et al.
Publicado: (2015)

Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor
por: Jacquemard, Célien, et al.
Publicado: (2021)

The first structure of HIV-1 gp120 with CD4 and CCR5 receptors
por: Guan, Yongjun
Publicado: (2019)

The Influence of N-Linked Glycans on the Molecular Dynamics of the HIV-1 gp120 V3 Loop
por: Wood, Natasha T., et al.
Publicado: (2013)

Forcefield_NCAA: Ab Initio Charge Parameters to Aid in the Discovery and Design of Therapeutic Proteins and Peptides with Unnatural Amino Acids and Their Application to Complement Inhibitors of the Compstatin Family
por: Khoury, George A., et al.
Publicado: (2014)

CXCR4 Recognition by L- and D-Peptides Containing the Full-Length V3 Loop of HIV-1 gp120
por: Zhu, Ruohan, et al.
Publicado: (2023)

Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage
por: Sander, Oliver, et al.
Publicado: (2007)

Structural Dynamics of HIV-1 Envelope Gp120 Outer Domain with V3 Loop
por: Yokoyama, Masaru, et al.
Publicado: (2012)

Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties
por: López de Victoria, Aliana, et al.
Publicado: (2012)

Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction
por: Grainger, David J, et al.
Publicado: (2005)

Curcumin improves synaptic plasticity impairment induced by HIV-1gp120 V3 loop
por: Shen, Ling-ling, et al.
Publicado: (2015)

Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
por: Rusert, Peter, et al.
Publicado: (2011)

Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5
por: Tam, Kayan, et al.
Publicado: (2016)

Focusing the immune response on the V3 loop of HIV-1 gp120 induces cross-clade neutralizing
por: Zolla-Pazner, Susan, et al.
Publicado: (2006)

Structure and Dynamics of the gp120 V3 Loop That Confers Noncompetitive Resistance in R5 HIV-1(JR-FL) to Maraviroc
por: Yuan, Yuzhe, et al.
Publicado: (2013)

Effect of Lysine to Arginine Mutagenesis in the V3 Loop of HIV-1 gp120 on Viral Entry Efficiency and Neutralization
por: Schwalbe, Birco, et al.
Publicado: (2015)

Computational study of HIV gp120 as a target for polyanionic entry inhibitors: Exploiting the V3 loop region
por: Hollingsworth, Louis R., et al.
Publicado: (2018)

Estimating the Threshold Surface Density of Gp120-CCR5 Complexes Necessary for HIV-1 Envelope-Mediated Cell-Cell Fusion
por: Mulampaka, Shiva Naresh, et al.
Publicado: (2011)

Cryptic Determinant of α4β7 Binding in the V2 Loop of HIV-1 gp120
por: Tassaneetrithep, Boonrat, et al.
Publicado: (2014)

Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
por: Masso, Majid, et al.
Publicado: (2010)

Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses
por: Bowder, Dane, et al.
Publicado: (2018)

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS
por: Sterjovski, Jasminka, et al.
Publicado: (2007)

Allosteric regulation by non peptidic, low molecular weight compounds of CCR5 coupling to g-proteins and interaction with Gp120 - consequences on inhibition of R5 HIV-1 infection
por: Rueda, Patricia, et al.
Publicado: (2010)

The C5 region of HIV-1 gp120 binds specific
por: Dalgleish, A, et al.
Publicado: (2006)

Interaction of Chemokine Receptor CCR5 with its Ligands: Multiple Domains for HIV-1 gp120 Binding and a Single Domain for Chemokine Binding
por: Wu, Lijun, et al.
Publicado: (1997)

Comparative determination of HIV-1 co-receptor tropism by Enhanced Sensitivity Trofile, gp120 V3-loop RNA and DNA genotyping
por: Prosperi, Mattia CF, et al.
Publicado: (2010)

The Molecular Basis of pH-Modulated HIV gp120 Binding Revealed
por: Morton, Scott P, et al.
Publicado: (2019)

Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers
por: de Taeye, Steven W., et al.
Publicado: (2018)

Internalization and Axonal Transport of the HIV Glycoprotein gp120
por: Berth, Sarah, et al.
Publicado: (2015)

Allosteric Modulation of the HIV-1 gp120-gp41 Association Site by Adjacent gp120 Variable Region 1 (V1) N-Glycans Linked to Neutralization Sensitivity
por: Drummer, Heidi E., et al.
Publicado: (2013)

Glycosylation Patterns of HIV-1 gp120 Depend on the Type of Expressing Cells and Affect Antibody Recognition
por: Raska, Milan, et al.
Publicado: (2010)

Conformation-dependent recognition of HIV Gp120 by DARPins provides novel possibilities to develop distinct HIV entry inhibitors
por: Mann, AM, et al.
Publicado: (2012)

Probing intrinsic dynamics and conformational transition of HIV gp120 by molecular dynamics simulation
por: Li, Yi, et al.
Publicado: (2020)

Study on molecular mechanisms of CD4 dependency and independency of HIV-1 gp120
por: Liu, Meng-Ting, et al.
Publicado: (2023)

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations
por: Roche, Michael, et al.
Publicado: (2013)

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape
por: Wibmer, Constantinos Kurt, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_uhripss8dck473k2tequo7sdjj