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In Trans Complementation of Lethal Factor Reveal Roles in Colonization and Dissemination in a Murine Mouse Model
Lethal factor (LF) is a component of the B. anthracis exotoxin and critical for pathogenesis. The roles of LF in early anthrax pathogenesis, such as colonization and dissemination from the initial site of infection, are poorly understood. In mice models of infection, LF-deficient strains either have...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999102/ https://www.ncbi.nlm.nih.gov/pubmed/24763227 http://dx.doi.org/10.1371/journal.pone.0095950 |