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Characterization of Genomic Vitamin D Receptor Binding Sites through Chromatin Looping and Opening
The vitamin D receptor (VDR) is a transcription factor that mediates the genomic effects of 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). Genome-wide there are several thousand binding sites and hundreds of primary 1,25(OH)(2)D(3) target genes, but their functional relation is largely elusive. In t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999108/ https://www.ncbi.nlm.nih.gov/pubmed/24763502 http://dx.doi.org/10.1371/journal.pone.0096184 |