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Rapid Response to Selection, Competitive Release and Increased Transmission Potential of Artesunate-Selected Plasmodium chabaudi Malaria Parasites
The evolution of drug resistance, a key challenge for our ability to treat and control infections, depends on two processes: de-novo resistance mutations, and the selection for and spread of resistant mutants within a population. Understanding the factors influencing the rates of these two processes...
Autores principales: | Pollitt, Laura C., Huijben, Silvie, Sim, Derek G., Salathé, Rahel M., Jones, Matthew J., Read, Andrew F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999151/ https://www.ncbi.nlm.nih.gov/pubmed/24763470 http://dx.doi.org/10.1371/journal.ppat.1004019 |
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