Cationic Antimicrobial Peptides Promote Microbial Mutagenesis and Pathoadaptation in Chronic Infections

Acquisition of adaptive mutations is essential for microbial persistence during chronic infections. This is particularly evident during chronic Pseudomonas aeruginosa lung infections in cystic fibrosis (CF) patients. Thus far, mutagenesis has been attributed to the generation of reactive species by...

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Detalles Bibliográficos
Autores principales: Limoli, Dominique H., Rockel, Andrea B., Host, Kurtis M., Jha, Anuvrat, Kopp, Benjamin T., Hollis, Thomas, Wozniak, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999168/
https://www.ncbi.nlm.nih.gov/pubmed/24763694
http://dx.doi.org/10.1371/journal.ppat.1004083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999168/
https://www.ncbi.nlm.nih.gov/pubmed/24763694
http://dx.doi.org/10.1371/journal.ppat.1004083

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