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Cationic Antimicrobial Peptides Promote Microbial Mutagenesis and Pathoadaptation in Chronic Infections
Acquisition of adaptive mutations is essential for microbial persistence during chronic infections. This is particularly evident during chronic Pseudomonas aeruginosa lung infections in cystic fibrosis (CF) patients. Thus far, mutagenesis has been attributed to the generation of reactive species by...
Autores principales: | Limoli, Dominique H., Rockel, Andrea B., Host, Kurtis M., Jha, Anuvrat, Kopp, Benjamin T., Hollis, Thomas, Wozniak, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999168/ https://www.ncbi.nlm.nih.gov/pubmed/24763694 http://dx.doi.org/10.1371/journal.ppat.1004083 |
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