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Noncanonical Role for the Host Vps4 AAA+ ATPase ESCRT Protein in the Formation of Tomato Bushy Stunt Virus Replicase

Assembling of the membrane-bound viral replicase complexes (VRCs) consisting of viral- and host-encoded proteins is a key step during the replication of positive-stranded RNA viruses in the infected cells. Previous genome-wide screens with Tomato bushy stunt tombusvirus (TBSV) in a yeast model host...

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Detalles Bibliográficos
Autores principales: Barajas, Daniel, Martín, Isabel Fernández de Castro, Pogany, Judit, Risco, Cristina, Nagy, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999190/
https://www.ncbi.nlm.nih.gov/pubmed/24763736
http://dx.doi.org/10.1371/journal.ppat.1004087