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JC Polyomavirus Infection Is Strongly Controlled by Human Leucocyte Antigen Class II Variants
JC polyomavirus (JCV) carriers with a compromised immune system, such as in HIV, or subjects on immune-modulating therapies, such as anti VLA-4 therapy may develop progressive multifocal leukoencephalopathy (PML) which is a lytic infection of oligodendrocytes in the brain. Serum antibodies to JCV ma...
Autores principales: | Sundqvist, Emilie, Buck, Dorothea, Warnke, Clemens, Albrecht, Eva, Gieger, Christian, Khademi, Mohsen, Lima Bomfim, Izaura, Fogdell-Hahn, Anna, Link, Jenny, Alfredsson, Lars, Søndergaard, Helle Bach, Hillert, Jan, Oturai, Annette B., Hemme, Bernhard, Kockum, Ingrid, Olsson, Tomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999271/ https://www.ncbi.nlm.nih.gov/pubmed/24763718 http://dx.doi.org/10.1371/journal.ppat.1004084 |
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