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Microtubule-targeting agents in oncology and therapeutic potential in hepatocellular carcinoma
In mammalian cells, microtubules are present both in interphase and dividing cells. In the latter, microtubules forming the mitotic spindle are highly dynamic and exquisitely sensitive to therapeutic inhibitors. Developed to alter microtubule function, microtubule-binding agents have been proven to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999274/ https://www.ncbi.nlm.nih.gov/pubmed/24790457 http://dx.doi.org/10.2147/OTT.S46019 |