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Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis
The desmosomal cadherin desmoglein-1 (DSG1) is an essential intercellular adhesion molecule that is altered in various human cutaneous disorders; however, its regulation and function in allergic disease remains unexplored. Herein, we demonstrate a specific reduction in DSG1 in esophageal biopsies fr...
Autores principales: | Sherrill, J D, KC, K, Wu, D, Djukic, Z, Caldwell, J M, Stucke, E M, Kemme, K A, Costello, M S, Mingler, M K, Blanchard, C, Collins, M H, Abonia, J P, Putnam, P E, Dellon, E S, Orlando, R C, Hogan, S P, Rothenb, M E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999291/ https://www.ncbi.nlm.nih.gov/pubmed/24220297 http://dx.doi.org/10.1038/mi.2013.90 |
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