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A Novel Gene Required for Male Fertility and Functional CATSPER Channel Formation in Spermatozoa
Calcium signaling is critical for successful fertilization. In spermatozoa, capacitation, hyperactivation of motility, and the acrosome reaction are all mediated by increases in intracellular Ca(2+). Cation channels of sperm proteins (CATSPERS1-4) form an alkalinization-activated Ca(2+)-selective ch...
Autores principales: | Chung, Jean-Ju, Navarro, Betsy, Krapivinsky, Grigory, Krapivinsky, Luba, Clapham, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999383/ https://www.ncbi.nlm.nih.gov/pubmed/21224844 http://dx.doi.org/10.1038/ncomms1153 |
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