Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes

Herein, we present three new 2,2’-bipyridines that carry two β-cyclodextrin moieties in different substitution patterns. When coordinated by zinc(II) or copper(I) ions (or their complexes), these compounds undergo conformational changes and switch between “open” and “closed” forms and thereby bringi...

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Autores principales: Kremer, Christopher, Schnakenburg, Gregor, Lützen, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999858/
https://www.ncbi.nlm.nih.gov/pubmed/24778736
http://dx.doi.org/10.3762/bjoc.10.77
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author Kremer, Christopher
Schnakenburg, Gregor
Lützen, Arne
author_facet Kremer, Christopher
Schnakenburg, Gregor
Lützen, Arne
author_sort Kremer, Christopher
collection PubMed
description Herein, we present three new 2,2’-bipyridines that carry two β-cyclodextrin moieties in different substitution patterns. When coordinated by zinc(II) or copper(I) ions (or their complexes), these compounds undergo conformational changes and switch between “open” and “closed” forms and thereby bringing together or separating the cyclodextrin moieties from each other.
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spelling pubmed-39998582014-04-28 Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes Kremer, Christopher Schnakenburg, Gregor Lützen, Arne Beilstein J Org Chem Full Research Paper Herein, we present three new 2,2’-bipyridines that carry two β-cyclodextrin moieties in different substitution patterns. When coordinated by zinc(II) or copper(I) ions (or their complexes), these compounds undergo conformational changes and switch between “open” and “closed” forms and thereby bringing together or separating the cyclodextrin moieties from each other. Beilstein-Institut 2014-04-09 /pmc/articles/PMC3999858/ /pubmed/24778736 http://dx.doi.org/10.3762/bjoc.10.77 Text en Copyright © 2014, Kremer et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Kremer, Christopher
Schnakenburg, Gregor
Lützen, Arne
Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes
title Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes
title_full Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes
title_fullStr Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes
title_full_unstemmed Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes
title_short Towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes
title_sort towards allosteric receptors – synthesis of β-cyclodextrin-functionalised 2,2’-bipyridines and their metal complexes
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999858/
https://www.ncbi.nlm.nih.gov/pubmed/24778736
http://dx.doi.org/10.3762/bjoc.10.77
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