Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide

Here we describe the use of a new open-source software package and a Raspberry Pi(®) computer for the simultaneous control of multiple flow chemistry devices and its application to a machine-assisted, multi-step flow preparation of pyrazine-2-carboxamide – a component of Rifater(®), used in the trea...

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Detalles Bibliográficos
Autores principales: Ingham, Richard J, Battilocchio, Claudio, Hawkins, Joel M, Ley, Steven V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999859/
https://www.ncbi.nlm.nih.gov/pubmed/24778715
http://dx.doi.org/10.3762/bjoc.10.56
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author Ingham, Richard J
Battilocchio, Claudio
Hawkins, Joel M
Ley, Steven V
author_facet Ingham, Richard J
Battilocchio, Claudio
Hawkins, Joel M
Ley, Steven V
author_sort Ingham, Richard J
collection PubMed
description Here we describe the use of a new open-source software package and a Raspberry Pi(®) computer for the simultaneous control of multiple flow chemistry devices and its application to a machine-assisted, multi-step flow preparation of pyrazine-2-carboxamide – a component of Rifater(®), used in the treatment of tuberculosis – and its reduced derivative piperazine-2-carboxamide.
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spelling pubmed-39998592014-04-28 Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide Ingham, Richard J Battilocchio, Claudio Hawkins, Joel M Ley, Steven V Beilstein J Org Chem Full Research Paper Here we describe the use of a new open-source software package and a Raspberry Pi(®) computer for the simultaneous control of multiple flow chemistry devices and its application to a machine-assisted, multi-step flow preparation of pyrazine-2-carboxamide – a component of Rifater(®), used in the treatment of tuberculosis – and its reduced derivative piperazine-2-carboxamide. Beilstein-Institut 2014-03-12 /pmc/articles/PMC3999859/ /pubmed/24778715 http://dx.doi.org/10.3762/bjoc.10.56 Text en Copyright © 2014, Ingham et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Ingham, Richard J
Battilocchio, Claudio
Hawkins, Joel M
Ley, Steven V
Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
title Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
title_full Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
title_fullStr Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
title_full_unstemmed Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
title_short Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
title_sort integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999859/
https://www.ncbi.nlm.nih.gov/pubmed/24778715
http://dx.doi.org/10.3762/bjoc.10.56
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