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Predicting HIV-1 broadly neutralizing antibody epitope networks using neutralization titers and a novel computational method

BACKGROUND: Recent efforts in HIV-1 vaccine design have focused on immunogens that evoke potent neutralizing antibody responses to a broad spectrum of viruses circulating worldwide. However, the development of effective vaccines will depend on the identification and characterization of the neutraliz...

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Detalles Bibliográficos
Autores principales: Evans, Mark C, Phung, Pham, Paquet, Agnes C, Parikh, Anvi, Petropoulos, Christos J, Wrin, Terri, Haddad, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999910/
https://www.ncbi.nlm.nih.gov/pubmed/24646213
http://dx.doi.org/10.1186/1471-2105-15-77