Severe acute respiratory syndrome-coronavirus infection in aged nonhuman primates is associated with modulated pulmonary and systemic immune responses

BACKGROUND: Many respiratory viruses disproportionately impact the elderly. Likewise, advanced age correlated with more adverse disease outcomes following severe acute respiratory syndrome coronavirus (SARS-CoV) infection in humans. We used an aged African green monkey SARS-CoV infection model to be...

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Detalles Bibliográficos
Autores principales: Clay, Candice C, Donart, Nathan, Fomukong, Ndingsa, Knight, Jennifer B, Overheim, Katie, Tipper, Jennifer, Van Westrienen, Jesse, Hahn, Fletcher, Harrod, Kevin S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999990/
https://www.ncbi.nlm.nih.gov/pubmed/24642138
http://dx.doi.org/10.1186/1742-4933-11-4

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