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GDF15 regulates Kv2.1-mediated outward K(+) current through the Akt/mTOR signalling pathway in rat cerebellar granule cells

GDF15 (growth/differentiation factor 15), a novel member of the TGFβ (transforming growth factor β) superfamily, plays critical roles in the central and peripheral nervous systems, but the signal transduction pathways and receptor subtypes involved are not well understood. In the present paper, we r...

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Detalles Bibliográficos
Autores principales: Wang, Chang-Ying, Huang, An-Qi, Zhou, Meng-Hua, Mei, Yan-Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000135/
https://www.ncbi.nlm.nih.gov/pubmed/24597762
http://dx.doi.org/10.1042/BJ20140155