Tumor necrosis factor receptor superfamily costimulation couples T cell receptor signal strength to thymic regulatory T cell differentiation

Regulatory T (T(reg)) cells express tumor necrosis factor receptor superfamily (TNFRSF) members, but their role in thymic T(reg) development is undefined. We demonstrate that T(reg) progenitors highly express the TNFRSF members GITR, OX40, and TNFR2. Expression of these receptors correlates directly...

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Detalles Bibliográficos
Autores principales: Mahmud, Shawn A., Manlove, Luke S., Schmitz, Heather M., Xing, Yan, Wang, Yanyan, Owen, David L., Schenkel, Jason M., Boomer, Jonathan S., Green, Jonathan M., Yagita, Hideo, Chi, Hongbo, Hogquist, Kristin A., Farrar, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000541/
https://www.ncbi.nlm.nih.gov/pubmed/24633226
http://dx.doi.org/10.1038/ni.2849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000541/
https://www.ncbi.nlm.nih.gov/pubmed/24633226
http://dx.doi.org/10.1038/ni.2849

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