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Tumor necrosis factor receptor superfamily costimulation couples T cell receptor signal strength to thymic regulatory T cell differentiation
Regulatory T (T(reg)) cells express tumor necrosis factor receptor superfamily (TNFRSF) members, but their role in thymic T(reg) development is undefined. We demonstrate that T(reg) progenitors highly express the TNFRSF members GITR, OX40, and TNFR2. Expression of these receptors correlates directly...
Autores principales: | Mahmud, Shawn A., Manlove, Luke S., Schmitz, Heather M., Xing, Yan, Wang, Yanyan, Owen, David L., Schenkel, Jason M., Boomer, Jonathan S., Green, Jonathan M., Yagita, Hideo, Chi, Hongbo, Hogquist, Kristin A., Farrar, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000541/ https://www.ncbi.nlm.nih.gov/pubmed/24633226 http://dx.doi.org/10.1038/ni.2849 |
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