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Promoter hypermethylation of tumor suppressor genes correlates with tumor grade and invasiveness in patients with urothelial bladder cancer

PURPOSE: To investigate the promoter methylation status at selected loci which encode for key proteins involved in apoptosis, DNA repair, cell cycle control and progression in urothelial cell carcinoma of bladder and compare the findings from tissue samples with that of plasma. METHODS: Total genomi...

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Detalles Bibliográficos
Autores principales: Bilgrami, Shumaila M, Qureshi, Sohail A, Pervez, Shahid, Abbas, Farhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000596/
https://www.ncbi.nlm.nih.gov/pubmed/24790823
http://dx.doi.org/10.1186/2193-1801-3-178