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Promoter hypermethylation of tumor suppressor genes correlates with tumor grade and invasiveness in patients with urothelial bladder cancer
PURPOSE: To investigate the promoter methylation status at selected loci which encode for key proteins involved in apoptosis, DNA repair, cell cycle control and progression in urothelial cell carcinoma of bladder and compare the findings from tissue samples with that of plasma. METHODS: Total genomi...
Autores principales: | Bilgrami, Shumaila M, Qureshi, Sohail A, Pervez, Shahid, Abbas, Farhat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000596/ https://www.ncbi.nlm.nih.gov/pubmed/24790823 http://dx.doi.org/10.1186/2193-1801-3-178 |
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