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Inhibition of autophagy enhances the cytotoxic effect of PA-MSHA in breast cancer

BACKGROUND: PA-MSHA, a genetically engineered Pseudomonas aeruginosa (PA) strain, is currently under investigation as a new anti-cancer drug. It can induce cell cycle arrest and apoptosis in different human cancer cells, including hormone receptor negative breast cancer cells. However, the underlyin...

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Detalles Bibliográficos
Autores principales: Xu, Wen-Huan, Liu, Zhe-Bin, Hou, Yi-Feng, Hong, Qi, Hu, Da-Li, Shao, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000616/
https://www.ncbi.nlm.nih.gov/pubmed/24745346
http://dx.doi.org/10.1186/1471-2407-14-273