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Testosterone Deficiency, Cardiac Health, and Older Men

Low levels of testosterone are manifested by erectile dysfunction, reduced sexual desire, and loss of morning erections with increasing numbers of men are being diagnosed and require treatment. The prevalence rates of testosterone deficiency vary according to different studies but may be as high as...

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Detalles Bibliográficos
Autores principales: Hackett, G., Kirby, M., Sinclair, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000629/
https://www.ncbi.nlm.nih.gov/pubmed/24812558
http://dx.doi.org/10.1155/2014/143763
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author Hackett, G.
Kirby, M.
Sinclair, A. J.
author_facet Hackett, G.
Kirby, M.
Sinclair, A. J.
author_sort Hackett, G.
collection PubMed
description Low levels of testosterone are manifested by erectile dysfunction, reduced sexual desire, and loss of morning erections with increasing numbers of men are being diagnosed and require treatment. The prevalence rates of testosterone deficiency vary according to different studies but may be as high as 40% in populations of patients with type 2 diabetes. There is increasing evidence that testosterone deficiency is associated with increased cardiovascular and all-cause mortality. Screening for low testosterone is recommended in a number of high risk groups including those with type 2 diabetes and metabolic syndrome. There are recent data to suggest that testosterone replacement therapy may reduce cardiovascular mortality as well as improving multiple surrogate markers for cardiovascular events. Specific clinical trials of testosterone replacement therapy are needed in selected populations but in the meantime we must treat patients based on the best current evidence.
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spelling pubmed-40006292014-05-08 Testosterone Deficiency, Cardiac Health, and Older Men Hackett, G. Kirby, M. Sinclair, A. J. Int J Endocrinol Review Article Low levels of testosterone are manifested by erectile dysfunction, reduced sexual desire, and loss of morning erections with increasing numbers of men are being diagnosed and require treatment. The prevalence rates of testosterone deficiency vary according to different studies but may be as high as 40% in populations of patients with type 2 diabetes. There is increasing evidence that testosterone deficiency is associated with increased cardiovascular and all-cause mortality. Screening for low testosterone is recommended in a number of high risk groups including those with type 2 diabetes and metabolic syndrome. There are recent data to suggest that testosterone replacement therapy may reduce cardiovascular mortality as well as improving multiple surrogate markers for cardiovascular events. Specific clinical trials of testosterone replacement therapy are needed in selected populations but in the meantime we must treat patients based on the best current evidence. Hindawi Publishing Corporation 2014 2014-04-10 /pmc/articles/PMC4000629/ /pubmed/24812558 http://dx.doi.org/10.1155/2014/143763 Text en Copyright © 2014 G. Hackett et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Hackett, G.
Kirby, M.
Sinclair, A. J.
Testosterone Deficiency, Cardiac Health, and Older Men
title Testosterone Deficiency, Cardiac Health, and Older Men
title_full Testosterone Deficiency, Cardiac Health, and Older Men
title_fullStr Testosterone Deficiency, Cardiac Health, and Older Men
title_full_unstemmed Testosterone Deficiency, Cardiac Health, and Older Men
title_short Testosterone Deficiency, Cardiac Health, and Older Men
title_sort testosterone deficiency, cardiac health, and older men
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000629/
https://www.ncbi.nlm.nih.gov/pubmed/24812558
http://dx.doi.org/10.1155/2014/143763
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