Notch prevents transforming growth factor-beta-assisted epithelial–mesenchymal transition in cultured limbal progenitor cells through the induction of Smad7

PURPOSE: Continuous culture of limbal epithelial stem cells (LSCs) slows down proliferation, which inevitably results in differentiation. Transforming growth factor-beta (TGFβ)-assisted epithelial–mesenchymal transition (EMT) is often found in the late stage of LSC culture. Thus, EMT is proposed to...

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Detalles Bibliográficos
Autores principales: Tsai, Tung-Han, Sun, Ming-Hui, Ho, Tsung-Chuan, Ma, Hsin-I., Liu, Ming-Ying, Tsao, Yeou-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000716/
https://www.ncbi.nlm.nih.gov/pubmed/24791137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000716/
https://www.ncbi.nlm.nih.gov/pubmed/24791137

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