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Outer Electrospun Polycaprolactone Shell Induces Massive Foreign Body Reaction and Impairs Axonal Regeneration through 3D Multichannel Chitosan Nerve Guides

We report on the performance of composite nerve grafts with an inner 3D multichannel porous chitosan core and an outer electrospun polycaprolactone shell. The inner chitosan core provided multiple guidance channels for regrowing axons. To analyze the in vivo properties of the bare chitosan cores, we...

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Detalles Bibliográficos
Autores principales:	Duda, Sven, Dreyer, Lutz, Behrens, Peter, Wienecke, Soenke, Chakradeo, Tanmay, Glasmacher, Birgit, Haastert-Talini, Kirsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000981/ https://www.ncbi.nlm.nih.gov/pubmed/24818158 http://dx.doi.org/10.1155/2014/835269

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