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DNA damage repair machinery and HIV escape from innate immune sensing

Viruses have been long known to perturb cell cycle regulators and key players of the DNA damage response to benefit their life cycles. In the case of the human immunodeficiency virus (HIV), the viral auxiliary protein Vpr activates the structure-specific endonuclease SLX4 complex to promote escape f...

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Detalles Bibliográficos
Autores principales: Brégnard, Christelle, Benkirane, Monsef, Laguette, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001025/
https://www.ncbi.nlm.nih.gov/pubmed/24795708
http://dx.doi.org/10.3389/fmicb.2014.00176

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