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Activating Killer Cell Ig-Like Receptors in Health and Disease

Expression of non-rearranged HLA class I-binding receptors characterizes human and mouse NK cells. The postulation of the missing-self hypothesis some 30 years ago triggered the subsequent search and discovery of inhibitory MHC-receptors, both in humans and mice. These receptors have two functions:...

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Detalles Bibliográficos
Autores principales: Ivarsson, Martin A., Michaëlsson, Jakob, Fauriat, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001058/
https://www.ncbi.nlm.nih.gov/pubmed/24795726
http://dx.doi.org/10.3389/fimmu.2014.00184