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Brain stimulation for intractable epilepsy: Anterior thalamus and responsive stimulation
Despite medications, resective surgery, and vagal nerve stimulation, some patients with epilepsy continue to have seizures. In these patients, other approaches are urgently needed. The biological basis of stimulation of anterior thalamic nucleus and epileptogenic focus is presented. Results from two...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001217/ https://www.ncbi.nlm.nih.gov/pubmed/24791096 http://dx.doi.org/10.4103/0972-2327.128671 |
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author | Krishna, Vibhor Lozano, Andres M. |
author_facet | Krishna, Vibhor Lozano, Andres M. |
author_sort | Krishna, Vibhor |
collection | PubMed |
description | Despite medications, resective surgery, and vagal nerve stimulation, some patients with epilepsy continue to have seizures. In these patients, other approaches are urgently needed. The biological basis of stimulation of anterior thalamic nucleus and epileptogenic focus is presented. Results from two large randomized controlled trials Stimulation of Anterior Nucleus of Thalamus for Epilepsy (SANTE) and Neuropace pivotal trial are discussed. Neuromodulation provides effective treatment for a select group of refractory epilepsy patients. Future investigations into the mechanism underlying ‘response’ to brain stimulation are desired. |
format | Online Article Text |
id | pubmed-4001217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-40012172014-05-01 Brain stimulation for intractable epilepsy: Anterior thalamus and responsive stimulation Krishna, Vibhor Lozano, Andres M. Ann Indian Acad Neurol Article Despite medications, resective surgery, and vagal nerve stimulation, some patients with epilepsy continue to have seizures. In these patients, other approaches are urgently needed. The biological basis of stimulation of anterior thalamic nucleus and epileptogenic focus is presented. Results from two large randomized controlled trials Stimulation of Anterior Nucleus of Thalamus for Epilepsy (SANTE) and Neuropace pivotal trial are discussed. Neuromodulation provides effective treatment for a select group of refractory epilepsy patients. Future investigations into the mechanism underlying ‘response’ to brain stimulation are desired. Medknow Publications & Media Pvt Ltd 2014-03 /pmc/articles/PMC4001217/ /pubmed/24791096 http://dx.doi.org/10.4103/0972-2327.128671 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Krishna, Vibhor Lozano, Andres M. Brain stimulation for intractable epilepsy: Anterior thalamus and responsive stimulation |
title | Brain stimulation for intractable epilepsy: Anterior thalamus and responsive stimulation |
title_full | Brain stimulation for intractable epilepsy: Anterior thalamus and responsive stimulation |
title_fullStr | Brain stimulation for intractable epilepsy: Anterior thalamus and responsive stimulation |
title_full_unstemmed | Brain stimulation for intractable epilepsy: Anterior thalamus and responsive stimulation |
title_short | Brain stimulation for intractable epilepsy: Anterior thalamus and responsive stimulation |
title_sort | brain stimulation for intractable epilepsy: anterior thalamus and responsive stimulation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001217/ https://www.ncbi.nlm.nih.gov/pubmed/24791096 http://dx.doi.org/10.4103/0972-2327.128671 |
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