Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation

Loss of the nucleus is a critical step in keratinocyte terminal differentiation. To elucidate the mechanisms involved, we focused on two characteristic events: nuclear translocation of N-terminal fragment of profilaggrin and caspase-14-dependent degradation of the inhibitor of caspase-activated DNas...

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Detalles Bibliográficos
Autores principales: Yamamoto-Tanaka, M, Makino, T, Motoyama, A, Miyai, M, Tsuboi, R, Hibino, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001300/
https://www.ncbi.nlm.nih.gov/pubmed/24743736
http://dx.doi.org/10.1038/cddis.2014.145

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