Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death

Many mitotic kinases are both critical for maintaining genome stability and are important targets for anticancer therapies. We provide evidence that SIK3 (salt-inducible kinase 3), an AMP-activated protein kinase-related kinase, is important for mitosis to occur properly in mammalian cells. Downregu...

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Detalles Bibliográficos
Autores principales: Chen, H, Huang, S, Han, X, Zhang, J, Shan, C, Tsang, Y H, Ma, H T, Poon, R Y C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001308/
https://www.ncbi.nlm.nih.gov/pubmed/24743732
http://dx.doi.org/10.1038/cddis.2014.154

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