Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death

The growing number of studies suggested that inhibition of autophagy enhances the efficacy of Akt kinase inhibitors in cancer therapy. Here, we provide evidence that ML-9, a widely used inhibitor of Akt kinase, myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1), represents t...

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Detalles Bibliográficos
Autores principales: Kondratskyi, A, Yassine, M, Slomianny, C, Kondratska, K, Gordienko, D, Dewailly, E, Lehen'kyi, V, Skryma, R, Prevarskaya, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001310/
https://www.ncbi.nlm.nih.gov/pubmed/24763050
http://dx.doi.org/10.1038/cddis.2014.156

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