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APPL proteins modulate DNA repair and radiation survival of pancreatic carcinoma cells by regulating ATM

Despite intensive multimodal therapies, the overall survival rate of patients with ductal adenocarcinoma of the pancreas is still poor. The chemo- and radioresistance mechanisms of this tumor entity remain to be determined in order to develop novel treatment strategies. In cancer, endocytosis and me...

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Detalles Bibliográficos
Autores principales:	Hennig, J, McShane, M P, Cordes, N, Eke, I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001316/ https://www.ncbi.nlm.nih.gov/pubmed/24763056 http://dx.doi.org/10.1038/cddis.2014.167

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