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A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis

We herein report a case of invasive micropapillary carcinoma (IMPC) involving extensive lymph node metastasis with no recurrence for over 7 years. A 41-year-old female presented with pain and a swelling mass in the left axillary region, which had been present for several months. The tumor measured 1...

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Autores principales: Taketani, Kenji, Tokunaga, Eriko, Yamashita, Nami, Tanaka, Kimihiro, Zaitsu, Yoko, Akiyoshi, Sayuri, Okada, Satoko, Aishima, Shinichi, Morita, Masaru, Maehara, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001353/
https://www.ncbi.nlm.nih.gov/pubmed/24708742
http://dx.doi.org/10.1186/1477-7819-12-84
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author Taketani, Kenji
Tokunaga, Eriko
Yamashita, Nami
Tanaka, Kimihiro
Zaitsu, Yoko
Akiyoshi, Sayuri
Okada, Satoko
Aishima, Shinichi
Morita, Masaru
Maehara, Yoshihiko
author_facet Taketani, Kenji
Tokunaga, Eriko
Yamashita, Nami
Tanaka, Kimihiro
Zaitsu, Yoko
Akiyoshi, Sayuri
Okada, Satoko
Aishima, Shinichi
Morita, Masaru
Maehara, Yoshihiko
author_sort Taketani, Kenji
collection PubMed
description We herein report a case of invasive micropapillary carcinoma (IMPC) involving extensive lymph node metastasis with no recurrence for over 7 years. A 41-year-old female presented with pain and a swelling mass in the left axillary region, which had been present for several months. The tumor measured 1.6 cm in diameter in the middle of upper area of the left breast. Based on the findings of a core needle biopsy the pathological diagnosis was IMPC or mucinous carcinoma. The cytology of the left axillary lymph node was positive for metastatic carcinoma. The patient underwent a left mastectomy and a left axillary dissection (level I to III). The postoperative pathological diagnosis was IMPC with mucin production, and the number of metastatic lymph nodes was 59. The patient was given adjuvant chemotherapy (four courses of 5-fluorouracil, epirubicin and cyclophosphamide (FEC) and four courses of docetaxel), radiation for the left chest wall, supraclavicular and internal thoracic area, and then received tamoxifen for 5 years. The patient has remained recurrence-free for over 7 years. IMPC is known to be an aggressive histological type associated with a high incidence of lymph node metastasis and a poor prognosis. It seems that long-term survival was obtained by performing sufficient medical treatment. Prognostic factors other than the number of lymph node metastases may also exist.
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spelling pubmed-40013532014-04-29 A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis Taketani, Kenji Tokunaga, Eriko Yamashita, Nami Tanaka, Kimihiro Zaitsu, Yoko Akiyoshi, Sayuri Okada, Satoko Aishima, Shinichi Morita, Masaru Maehara, Yoshihiko World J Surg Oncol Case Report We herein report a case of invasive micropapillary carcinoma (IMPC) involving extensive lymph node metastasis with no recurrence for over 7 years. A 41-year-old female presented with pain and a swelling mass in the left axillary region, which had been present for several months. The tumor measured 1.6 cm in diameter in the middle of upper area of the left breast. Based on the findings of a core needle biopsy the pathological diagnosis was IMPC or mucinous carcinoma. The cytology of the left axillary lymph node was positive for metastatic carcinoma. The patient underwent a left mastectomy and a left axillary dissection (level I to III). The postoperative pathological diagnosis was IMPC with mucin production, and the number of metastatic lymph nodes was 59. The patient was given adjuvant chemotherapy (four courses of 5-fluorouracil, epirubicin and cyclophosphamide (FEC) and four courses of docetaxel), radiation for the left chest wall, supraclavicular and internal thoracic area, and then received tamoxifen for 5 years. The patient has remained recurrence-free for over 7 years. IMPC is known to be an aggressive histological type associated with a high incidence of lymph node metastasis and a poor prognosis. It seems that long-term survival was obtained by performing sufficient medical treatment. Prognostic factors other than the number of lymph node metastases may also exist. BioMed Central 2014-04-04 /pmc/articles/PMC4001353/ /pubmed/24708742 http://dx.doi.org/10.1186/1477-7819-12-84 Text en Copyright © 2014 Taketani et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Case Report
Taketani, Kenji
Tokunaga, Eriko
Yamashita, Nami
Tanaka, Kimihiro
Zaitsu, Yoko
Akiyoshi, Sayuri
Okada, Satoko
Aishima, Shinichi
Morita, Masaru
Maehara, Yoshihiko
A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis
title A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis
title_full A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis
title_fullStr A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis
title_full_unstemmed A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis
title_short A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis
title_sort case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001353/
https://www.ncbi.nlm.nih.gov/pubmed/24708742
http://dx.doi.org/10.1186/1477-7819-12-84
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