Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus

BACKGROUND: Diabetes is a significant risk factor for developing West Nile virus (WNV)-associated encephalitis (WNVE) in humans, the leading cause of arboviral encephalitis in the United States. Using a diabetic mouse model (db/db), we recently demonstrated that diabetes enhanced WNV replication and...

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Detalles Bibliográficos
Autores principales: Kumar, Mukesh, Roe, Kelsey, Nerurkar, Pratibha V, Orillo, Beverly, Thompson, Karen S, Verma, Saguna, Nerurkar, Vivek R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001407/
https://www.ncbi.nlm.nih.gov/pubmed/24750819
http://dx.doi.org/10.1186/1742-2094-11-80

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