Evolutionary imprint of activation: The design principles of VSDs

Voltage-sensor domains (VSDs) are modular biomolecular machines that transduce electrical signals in cells through a highly conserved activation mechanism. Here, we investigate sequence–function relationships in VSDs with approaches from information theory and probabilistic modeling. Specifically, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Palovcak, Eugene, Delemotte, Lucie, Klein, Michael L., Carnevale, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001776/
https://www.ncbi.nlm.nih.gov/pubmed/24470486
http://dx.doi.org/10.1085/jgp.201311103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001776/
https://www.ncbi.nlm.nih.gov/pubmed/24470486
http://dx.doi.org/10.1085/jgp.201311103

Ejemplares similares