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Functional differences of Porphyromonas gingivalis Fimbriae in determining periodontal disease pathogenesis: a literature review
Porphyromonas gingivalis is implicated in chronic and aggressive periodontitis. This bacterium has numerous virulence factors and one is the Fimbriae, which is quite important for bacterial colonization. Fimbriae are appendices that anchor to the bacterial wall and are comprised of the protein FimBr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Universidad del Valle
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002014/ https://www.ncbi.nlm.nih.gov/pubmed/24892323 |
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author | Moreno, Sandra Contreras, Adolfo |
author_facet | Moreno, Sandra Contreras, Adolfo |
author_sort | Moreno, Sandra |
collection | PubMed |
description | Porphyromonas gingivalis is implicated in chronic and aggressive periodontitis. This bacterium has numerous virulence factors and one is the Fimbriae, which is quite important for bacterial colonization. Fimbriae are appendices that anchor to the bacterial wall and are comprised of the protein FimBriline encoded by the FimA gene. Thus far, six genotypes have been identified, FimA I to V and Ib. Genotypes II and IV are associated with periodontal disease, while genotype I is related to gingival health. Genotype identification of P. gingivalis FimA in periodontitis would be important to confirm the pathogenic genotypes and to establish risk at population level. This review is about the P. gingivalis FimA genotype prevalence worldwide. A systematic search using Pubmed, Hinary, and Science Direct within the following descriptors: Porphyromonas gingivalis, bacterial adhesion, periodontitis, Fimbriae, FimA, genotipification was performed to April 2011. |
format | Online Article Text |
id | pubmed-4002014 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Universidad del Valle |
record_format | MEDLINE/PubMed |
spelling | pubmed-40020142014-06-02 Functional differences of Porphyromonas gingivalis Fimbriae in determining periodontal disease pathogenesis: a literature review Moreno, Sandra Contreras, Adolfo Colomb Med (Cali) Review Article Porphyromonas gingivalis is implicated in chronic and aggressive periodontitis. This bacterium has numerous virulence factors and one is the Fimbriae, which is quite important for bacterial colonization. Fimbriae are appendices that anchor to the bacterial wall and are comprised of the protein FimBriline encoded by the FimA gene. Thus far, six genotypes have been identified, FimA I to V and Ib. Genotypes II and IV are associated with periodontal disease, while genotype I is related to gingival health. Genotype identification of P. gingivalis FimA in periodontitis would be important to confirm the pathogenic genotypes and to establish risk at population level. This review is about the P. gingivalis FimA genotype prevalence worldwide. A systematic search using Pubmed, Hinary, and Science Direct within the following descriptors: Porphyromonas gingivalis, bacterial adhesion, periodontitis, Fimbriae, FimA, genotipification was performed to April 2011. Universidad del Valle 2013-03-30 /pmc/articles/PMC4002014/ /pubmed/24892323 Text en Copyright: © 2013 Universidad del Valle. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Moreno, Sandra Contreras, Adolfo Functional differences of Porphyromonas gingivalis Fimbriae in determining periodontal disease pathogenesis: a literature review |
title | Functional differences of Porphyromonas gingivalis
Fimbriae in determining periodontal disease pathogenesis: a literature review |
title_full | Functional differences of Porphyromonas gingivalis
Fimbriae in determining periodontal disease pathogenesis: a literature review |
title_fullStr | Functional differences of Porphyromonas gingivalis
Fimbriae in determining periodontal disease pathogenesis: a literature review |
title_full_unstemmed | Functional differences of Porphyromonas gingivalis
Fimbriae in determining periodontal disease pathogenesis: a literature review |
title_short | Functional differences of Porphyromonas gingivalis
Fimbriae in determining periodontal disease pathogenesis: a literature review |
title_sort | functional differences of porphyromonas gingivalis
fimbriae in determining periodontal disease pathogenesis: a literature review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002014/ https://www.ncbi.nlm.nih.gov/pubmed/24892323 |
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