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Albendazole-induced liver injury: a case report
We report a case of a 47-year-old male, who was referred to the clinical hepatology services at Pablo Tobón Uribe Hospital for evaluation of a jaundice syndrome. After undergoing several exams, we diagnosed hepatic hydatidosis and the patient was treated with albendazole; however, after five months...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Universidad del Valle
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002020/ https://www.ncbi.nlm.nih.gov/pubmed/24892458 |
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author | Ríos, David Restrepo, Juan C |
author_facet | Ríos, David Restrepo, Juan C |
author_sort | Ríos, David |
collection | PubMed |
description | We report a case of a 47-year-old male, who was referred to the clinical hepatology services at Pablo Tobón Uribe Hospital for evaluation of a jaundice syndrome. After undergoing several exams, we diagnosed hepatic hydatidosis and the patient was treated with albendazole; however, after five months of uninterrupted treatment the patient again consulted and his liver test showed marked hepatocellular damage. This time, the patient was diagnosed with drug-induced liver injury due to albendazole, based on information from the clinical record, history of drug consumption, clinical and laboratory tests improved after discontinuing the medication and after discarding other possible causes; this diagnosis was supported by the CIOMS/RUCAM scale, which showed a "likely" correlation between hepatocellular damage and drug toxicity etiology. |
format | Online Article Text |
id | pubmed-4002020 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Universidad del Valle |
record_format | MEDLINE/PubMed |
spelling | pubmed-40020202014-06-02 Albendazole-induced liver injury: a case report Ríos, David Restrepo, Juan C Colomb Med (Cali) Original Article We report a case of a 47-year-old male, who was referred to the clinical hepatology services at Pablo Tobón Uribe Hospital for evaluation of a jaundice syndrome. After undergoing several exams, we diagnosed hepatic hydatidosis and the patient was treated with albendazole; however, after five months of uninterrupted treatment the patient again consulted and his liver test showed marked hepatocellular damage. This time, the patient was diagnosed with drug-induced liver injury due to albendazole, based on information from the clinical record, history of drug consumption, clinical and laboratory tests improved after discontinuing the medication and after discarding other possible causes; this diagnosis was supported by the CIOMS/RUCAM scale, which showed a "likely" correlation between hepatocellular damage and drug toxicity etiology. Universidad del Valle 2013-06-30 /pmc/articles/PMC4002020/ /pubmed/24892458 Text en Copyright: © 2013 Universidad del Valle. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Ríos, David Restrepo, Juan C Albendazole-induced liver injury: a case report |
title | Albendazole-induced liver injury: a case report |
title_full | Albendazole-induced liver injury: a case report |
title_fullStr | Albendazole-induced liver injury: a case report |
title_full_unstemmed | Albendazole-induced liver injury: a case report |
title_short | Albendazole-induced liver injury: a case report |
title_sort | albendazole-induced liver injury: a case report |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002020/ https://www.ncbi.nlm.nih.gov/pubmed/24892458 |
work_keys_str_mv | AT riosdavid albendazoleinducedliverinjuryacasereport AT restrepojuanc albendazoleinducedliverinjuryacasereport |