Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein

PRDM9 (PR domain-containing protein 9) is a meiosis-specific protein that trimethylates H3K4 and controls the activation of recombination hot spots. It is an essential enzyme in the progression of early meiotic prophase. Disruption of the PRDM9 gene results in sterility in mice. In human, several PR...

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Detalles Bibliográficos
Autores principales: Eram, Mohammad S., Bustos, Susan P., Lima-Fernandes, Evelyne, Siarheyeva, Alena, Senisterra, Guillermo, Hajian, Taraneh, Chau, Irene, Duan, Shili, Wu, Hong, Dombrovski, Ludmila, Schapira, Matthieu, Arrowsmith, Cheryl H., Vedadi, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002121/
https://www.ncbi.nlm.nih.gov/pubmed/24634223
http://dx.doi.org/10.1074/jbc.M113.523183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002121/
https://www.ncbi.nlm.nih.gov/pubmed/24634223
http://dx.doi.org/10.1074/jbc.M113.523183

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