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Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1‐dependent mechanism in skeletal muscle cells

Amino acid transporters (AATs) provide a link between amino acid availability and mammalian/mechanistic target of rapamycin complex 1 (mTORC1) activation although the direct relationship remains unclear. Previous studies in various cell types have used high insulin concentrations to determine the ro...

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Detalles Bibliográficos
Autores principales:	Walker, Dillon K., Drummond, Micah J., Dickinson, Jared M., Borack, Michael S., Jennings, Kristofer, Volpi, Elena, Rasmussen, Blake B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002227/ https://www.ncbi.nlm.nih.gov/pubmed/24760501 http://dx.doi.org/10.1002/phy2.238

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