Clinical Significance of Atypical Glandular Cells in the Bethesda System 2001: A Comparison with the Histopathological Diagnosis of Surgically Resected Specimens

Forty-one patients diagnosed with atypical glangular cells (AGC) underwent surgery, and the histopathological diagnosis results for the resected specimens and the clinical features were analyzed. Out of 41 patients, final pathological diagnosis was endometrial cancer in 13 patients, cervical adenoca...

Descripción completa

Detalles Bibliográficos
Autores principales: Shoji, Tadahiro, Takatori, Eriko, Takeuchi, Satoshi, Yoshizaki, Akira, Uesugi, Noriyuki, Sugai, Tamotsu, Sugiyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002635/
https://www.ncbi.nlm.nih.gov/pubmed/24576221
http://dx.doi.org/10.3109/07357907.2014.880453
_version_ 1782313815889674240
author Shoji, Tadahiro
Takatori, Eriko
Takeuchi, Satoshi
Yoshizaki, Akira
Uesugi, Noriyuki
Sugai, Tamotsu
Sugiyama, Toru
author_facet Shoji, Tadahiro
Takatori, Eriko
Takeuchi, Satoshi
Yoshizaki, Akira
Uesugi, Noriyuki
Sugai, Tamotsu
Sugiyama, Toru
author_sort Shoji, Tadahiro
collection PubMed
description Forty-one patients diagnosed with atypical glangular cells (AGC) underwent surgery, and the histopathological diagnosis results for the resected specimens and the clinical features were analyzed. Out of 41 patients, final pathological diagnosis was endometrial cancer in 13 patients, cervical adenocarcinoma in 8, AIS in 7, CIN3 in 6, others in 2, and no lesions in 5. In comparison with previous reports, malignant or premalignant lesions were detected more frequently in patients with AGC who underwent surgery. We believe that conization or hysterectomy aimed at diagnosis and treatment, as well as endometrial histodiagnosis, should be carried out aggressively in patients with AGC.
format Online
Article
Text
id pubmed-4002635
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Informa Healthcare
record_format MEDLINE/PubMed
spelling pubmed-40026352014-05-06 Clinical Significance of Atypical Glandular Cells in the Bethesda System 2001: A Comparison with the Histopathological Diagnosis of Surgically Resected Specimens Shoji, Tadahiro Takatori, Eriko Takeuchi, Satoshi Yoshizaki, Akira Uesugi, Noriyuki Sugai, Tamotsu Sugiyama, Toru Cancer Invest Original Article Forty-one patients diagnosed with atypical glangular cells (AGC) underwent surgery, and the histopathological diagnosis results for the resected specimens and the clinical features were analyzed. Out of 41 patients, final pathological diagnosis was endometrial cancer in 13 patients, cervical adenocarcinoma in 8, AIS in 7, CIN3 in 6, others in 2, and no lesions in 5. In comparison with previous reports, malignant or premalignant lesions were detected more frequently in patients with AGC who underwent surgery. We believe that conization or hysterectomy aimed at diagnosis and treatment, as well as endometrial histodiagnosis, should be carried out aggressively in patients with AGC. Informa Healthcare 2014-05 2014-02-27 /pmc/articles/PMC4002635/ /pubmed/24576221 http://dx.doi.org/10.3109/07357907.2014.880453 Text en © The Author(s) http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited.
spellingShingle Original Article
Shoji, Tadahiro
Takatori, Eriko
Takeuchi, Satoshi
Yoshizaki, Akira
Uesugi, Noriyuki
Sugai, Tamotsu
Sugiyama, Toru
Clinical Significance of Atypical Glandular Cells in the Bethesda System 2001: A Comparison with the Histopathological Diagnosis of Surgically Resected Specimens
title Clinical Significance of Atypical Glandular Cells in the Bethesda System 2001: A Comparison with the Histopathological Diagnosis of Surgically Resected Specimens
title_full Clinical Significance of Atypical Glandular Cells in the Bethesda System 2001: A Comparison with the Histopathological Diagnosis of Surgically Resected Specimens
title_fullStr Clinical Significance of Atypical Glandular Cells in the Bethesda System 2001: A Comparison with the Histopathological Diagnosis of Surgically Resected Specimens
title_full_unstemmed Clinical Significance of Atypical Glandular Cells in the Bethesda System 2001: A Comparison with the Histopathological Diagnosis of Surgically Resected Specimens
title_short Clinical Significance of Atypical Glandular Cells in the Bethesda System 2001: A Comparison with the Histopathological Diagnosis of Surgically Resected Specimens
title_sort clinical significance of atypical glandular cells in the bethesda system 2001: a comparison with the histopathological diagnosis of surgically resected specimens
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002635/
https://www.ncbi.nlm.nih.gov/pubmed/24576221
http://dx.doi.org/10.3109/07357907.2014.880453
work_keys_str_mv AT shojitadahiro clinicalsignificanceofatypicalglandularcellsinthebethesdasystem2001acomparisonwiththehistopathologicaldiagnosisofsurgicallyresectedspecimens
AT takatorieriko clinicalsignificanceofatypicalglandularcellsinthebethesdasystem2001acomparisonwiththehistopathologicaldiagnosisofsurgicallyresectedspecimens
AT takeuchisatoshi clinicalsignificanceofatypicalglandularcellsinthebethesdasystem2001acomparisonwiththehistopathologicaldiagnosisofsurgicallyresectedspecimens
AT yoshizakiakira clinicalsignificanceofatypicalglandularcellsinthebethesdasystem2001acomparisonwiththehistopathologicaldiagnosisofsurgicallyresectedspecimens
AT uesuginoriyuki clinicalsignificanceofatypicalglandularcellsinthebethesdasystem2001acomparisonwiththehistopathologicaldiagnosisofsurgicallyresectedspecimens
AT sugaitamotsu clinicalsignificanceofatypicalglandularcellsinthebethesdasystem2001acomparisonwiththehistopathologicaldiagnosisofsurgicallyresectedspecimens
AT sugiyamatoru clinicalsignificanceofatypicalglandularcellsinthebethesdasystem2001acomparisonwiththehistopathologicaldiagnosisofsurgicallyresectedspecimens

Ejemplares similares