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Hepatitis B spliced protein (HBSP) promotes the carcinogenic effects of benzo [alpha] pyrene by interacting with microsomal epoxide hydrolase and enhancing its hydrolysis activity

BACKGROUND: The risk of hepatocellular carcinoma (HCC) increases in chronic hepatitis B surface antigen (HBsAg) carriers who often have concomitant increase in the levels of benzo[alpha]pyrene-7,8-diol-9,10-epoxide(±) (BPDE)-DNA adduct in liver tissues, suggesting a possible co-carcinogenesis of Hep...

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Detalles Bibliográficos
Autores principales:	Chen, Jin-Yan, Chen, Wan-Nan, Jiao, Bo-Yan, Lin, Wan-Song, Wu, Yun-Li, Liu, Ling-Ling, Lin, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002904/ https://www.ncbi.nlm.nih.gov/pubmed/24758376 http://dx.doi.org/10.1186/1471-2407-14-282

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