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Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

Voltage-gated sodium (Na(V)) channels mediate electrical excitability in animals. Despite strong sequence conservation among the voltage-sensor domains (VSDs) of closely related voltage-gated potassium (K(V)) and Na(V) channels, the functional contributions of individual side chains in Na(v) VSDs re...

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Detalles Bibliográficos
Autores principales:	Pless, Stephan A., Elstone, Fisal D., Niciforovic, Ana P., Galpin, Jason D., Yang, Runying, Kurata, Harley T., Ahern, Christopher A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003186/ https://www.ncbi.nlm.nih.gov/pubmed/24778431 http://dx.doi.org/10.1085/jgp.201311036

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