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State-dependent and site-directed photodynamic transformation of HCN2 channel by singlet oxygen
Singlet oxygen ((1)O(2)), which is generated through metabolic reactions and oxidizes numerous biological molecules, has been a useful tool in basic research and clinical practice. However, its role as a signaling factor, as well as a mechanistic understanding of the oxidation process, remains poorl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003188/ https://www.ncbi.nlm.nih.gov/pubmed/24733837 http://dx.doi.org/10.1085/jgp.201311112 |